叶兴国

叶兴国

职　　称

研究员

电　　话

82105173

电子邮件

yexingguo@caad.cn

创新团队

作物转基因及基因编辑技术与应用

研究组

植物转基因技术研究中心

研究中心

作物基因与分子设计中心

组　　员：

王轲，杜丽璞
唐华丽

研究生

Alia Anwar，石磊，刘会云，陈海强，唐华丽，贾子苗，邱玉亮，胡金鑫
Bisma Riaz，于美，常亚南，韩志阳

教育经历

1980年7月---1984年8月：宁夏农学院农学专业，获学士学位；1988年8月-1991年7月：中国农业农业科学院研究生院作物遗传育种专业，获硕士学位；1991年8月-1994年7月：中国农业农业科学院研究生院作物遗传育种专业，获博士学位。

工作经历

1984年7月-1988年8月：宁夏农林科学院作物研究所，实习研究员；1994年7月-1997年12月：中国农业农业科学院作物育种栽培研究所，助理研究员；1997年2月-1998年3月：韩国高丽大学生物技术学院，访问学者；1998年3月-2003年12月：中国农业农业科学院作物科学研究所，副研究员；2000年5-10月：美国内布拉斯加大学生物技术中心，访问学者；2001年7月-2002年12月：美国内布拉斯加大学生物技术中心，博士后；2003年4-10月，2003年4-10月：美国内布拉斯加大学生物技术中心，访问学者；2004年1月-现在：中国农业农业科学院作物科学研究所，研究员。

研究方向

小麦细胞染色体工程和基因工程育种，包括小麦小麦转基因体系和单倍体诱导体系建立、小麦近缘种属染色体标记开发、小麦再生相关基因克隆和小麦新品种培育等。

学术兼职

BMC Plant Biology、Frontiers in Plant Science、Agriculture、BMC Genomics、作物杂志和科技导报编委。

荣誉称号

中国农业科学院作物科学研究所中青年骨干人才

获奖成果

北京市科技进步一等奖1项，中国农业科学院科技进步一等奖1项，宁夏回族自治区科技进步二等奖和三等奖各1项。

承担项目

国家自然科学基金5项，宁夏回族自治区重点研发计划1项，国家重点研发计划子课题1项，国家转基因重大专项子课题3项，中日中澳国际合作课题各1项。

审定品种

宁春42号，宁春50号，宁春63号，宁春66号。

主要论文

Qiu YL, Han ZY, Liu NT, Yu M, Zhang SX, Chen HQ, Tang HL, Zhao ZY, Wang K, Lin ZS, Han FP*, Ye XG*. Effects of Aegilops longissima chromosome 1Sl on wheat bread-making quality in two types of translocation lines. Theor Appl Genet, 2024, 137: 2.下载
Tang HL, Wang K, Zhang SX, Han ZY, Chang YN, Qiu YL, Yu M, Du LP, Ye XG*. A fast technique for visual screening of wheat haploids generated from TaMTL-edited mutants carrying anthocyanin markers. Plant Comm, 2023, 4: 100569.下载
Guo XR, Shi QH, Wang M, Yuan J, Zhang J, Wang J, Liu Y, Su HD, Wang Z, Li J, Liu C, Ye XG*, Han FH*. Functional analysis of the glutathione S-transferases from Thinopyrum and its derivatives on wheat Fusarium head blight resistance. Plant Biotechnol J, 2023, https://doi.org/10.1111/pbi.14021.下载

Tang HL, Qiu YL, Wang WX, Yu M, Cang YN, Han ZY, Du LP, Lin ZS, Wang K*, Ye XG*. Development of a haploid-inducer by editing HvMTL in barley. J Genet Genom, 2023, 50(5): 366-369.下载
Liang XN, Bie XM, Qiu YL, Wang K, Yang ZJ, Jia YQ, Xu ZY, Yu M, Du LP, Lin ZS*, Ye XG*. Development of powdery mildew resistant derivatives of wheat variety Fielder for use in genetic transformation. Crop J, 2023, 11(2): 573-583.下载
Liu HY, Ma HL, Zhang W, Wang WQ, Wu JJ, Lin ZS*, Ye XG*. Identification of three wheat near isogenic lines originated from CB037 on tissue culture and transformation capacities. Plant Cell Tiss Org Cult, 2023, 152: 67-79.下载
Wang K*, Shi L, Liang X, Zhao P, Wang W, Liu J, Chang Y, Hiei Y, Yanagihara C, Du L, Ishida Y*, Ye XG*. The gene TaWOX5 overcomes genotype dependency in wheat genetic transformation. Nat Plant, 2022, 8: 110-117.下载
Qiu YL, Chen HQ, Zhang SX, Wang J, Du LP, Wang K*, Ye XG*. Development of a wheat material with improved bread-making quality by overexpressing HMW-GS 1Slx2.3* from Aegilops longissimi. Crop J, 2022, 10(6): 1717-1726.下载
Ma XL, Chang YN, Cheng JN, Yu M, Wang BC, Ye XG*, Lin ZS*. Development of wheat-Dasypyrum villosum T6V#4S·6AL translocation lines with enhanced inheritance for powdery mildew resistance. Theor Appl Genet, 2022, 135: 2423-2435下载
Hu JX, Yu Mei, Chang YN, Tang HL, Wang WX, Du LP, Wang K*, Yan YM*, Ye XG*. Functional analysis of TaPDI genes on storage protein accumulation by CRISPR/Cas9 edited wheat mutants. Int J Biol Macromol, 2022, 196: 131-143.下载
Tang HL, Liu HY, Zhou Y, Liu HW, Du LP, Wang K*, Ye XG*. Fertility recovery of wheat male sterility controlled by Ms2 using CRISPR/Cas9. Plant Biotechnol J, 2021, 19: 224-226.下载
Alia A, Wang K, Wang J, Shi L, Du LP, Ye XG*. Expression of Arabidopsis ornithine aminotransferase (AtOAT) encoded gene enhances multiple abiotic stress tolerances in wheat. Plant Cell Rep, 2021, 40: 1155-1170.下载
Liu HY, Wang K*, Jia ZM, Gong Q, Lin ZS, Du LP, Pei XW, Ye XG*. Editing TaMTL gene induces haploid plants efficiently by optimized Agrobacterium-mediated CRISPR system in wheat. Journal of Experimental Botany, 2020, 71: 1337-1349下载
Chen HQ, Li SJ, Liu YW, Liu JX, Ma XL, Du LP, Wang K, Ye XG*. Effects of 1Dy12 subunit silencing on seed storage protein accumulation and flour-processing quality in a common wheat somatic variation line. Food Chemistry, 2020, 335: 127663.下载
Li SJ, Jia ZM, Wang K, Du LP, Li HJ, Lin ZS*, Ye XG*. Screening and functional characterization of candidate resistance genes to powdery mildew from Dasypyrum villosum#4 in a wheat line Pm97033. Theor Appl Genet, 2020, 133: 3067-3083.下载
Liang QJ, Wang K, Shariful I, Ye XG*, Zhang CY*. Folate content and retention in wheat grains and wheat-based foods: Effects of storage, processing, and cooking methods. Food Chemistry, 2020, 333: 127459.下载
Liu HY, Wang K, Tang HL, Gong Q, Du LP, Pei XW*, Ye XG*. CRISPR/Cas9 editing of wheat TaQ genes alters spike morphogenesis and grain threshability. J Genet Genom, 2020, 47: 563-575.下载
Alia A, She MY, Wang K, Ye XG*. Cloning and molecular characterization of Triticum aestivum ornithine amino transferase (TaOAT) encoding genes. BMC Plant Biology, 2020 20:187.下载
Liu HY, Wang K, Wang J, Du LP, Pei XW, Ye XG. Genetic and agronomic traits stability of marker-free transgenic wheat plants generated from Agrobacterium mediated co-transformation in T2 and T3 generation. Journal of Integrative Agriculture, 2020, 19: 23-32.下载
Bisma R, Liang QJ, Wan X, Wang K, Zhang CY×, Ye XG×. Folate content analysis of wheat cultivars developed in the North China Plain. Food Chemistry, 2019, 289: 377-383.下载
Liang QJ,Wang K, Liu XL, Bisma R, Jiang L, Wan X, Ye XG*, Zhang CY*. Improved folate accumulation in genetically modified maize and wheat. Journal of Experimental Botany, 2019, 70: 1539-1551.下载
Wang K, Gong Q, and Ye XG*. Recent developments and applications of genetic transformation and genome editing technologies in wheat. Theor Appl Genet, 2019, doi.org/10.1007/s00122-019-03464-4.下载
Wang J, Liu C, Guo XR, Wang K, Du LP, Lin ZS*, Ye XG.* Development and genetic analysis of wheat double substitution lines carrying Hordeum vulgare 2H and Thinopyrum intermedium 2Ai#2 chromosomes. Crop J, 2019, 6: 22-31.下载
Li SJ, Wang J, Wang KY, Chen JN, Wang K, Du LP, Nin ZF, Lin ZS*, Ye XG*. Development of PCR markers specific to Dasypyrum villosum genome based on transcriptome data and their application in breeding Triticum aestivum-D. villosum#4 alien chromosome lines. BMC Genom, 2019, 20: 289.下载
Riaz B, Chen HQ, Wang J, Du LP, Wang K*, Ye XG*. Overexpression of maize ZmC1 and ZmR transcription factors in wheat regulates anthocyanin biosynthesis in a tissue-specific manner. Int J Mol Sci, 2019, 20: 5806.下载
Ye XG*, Zhang SX*, Li SJ, Wang J, Chen HQ, Wang K, Lin ZS, Wei YQ, Du LP,Yan YM*. Improvement of three commercial spring wheat varieties for powdery mildew resistance by marker-assisted selection. Crop Protection, 2019, 125: 104889.下载
Alia A, She MY, Wang K, Bisma R, Ye XG*. Biological roles of ornithine aminotransferase (OAT) in plant stress tolerance: Present progress and future perspectives. Int J Mol Sci, 2018, 19: 3681.下载
Wang KY, Lin ZS, Wang L, Wang K, Shi QH, Du LP, Ye XG*. Development of a set of PCR markers specific to Aegilops longissima chromosome arms and application in breeding a translocation line. Theor Appl Genet, 2018, 131: 13-25.下载
Wang K, Riaz B, Ye XG*. Wheat genome editing expedited by efficient transformation techniques: progress and perspectives. The Crop Journal, 2018, 6(1): 22-31.下载
Li SJ, Lin ZS, Liu C, Wang K, Du LP, Ye XG*. Development and comparative genomic mapping of Dasypyrum villosum 6V#4S-specific PCR markers using transcriptome data. Theor Appl Genet, 2017, 130: 2057-2068.下载
Wang K, Liu HY, Du LP, Ye XG*. Generation of marker-free transgenic hexaploid wheat via an Agrobacterium-mediated co-transformation strategy in commercial Chinese wheat varieties. Plant Biotechnology Journal, 2017, 15: 614-623.下载
She MY, Wang J, Wang XM, Yin GX, Wang K, Du LP, Ye XG*. Comprehensive molecular analysis of arginase-encoding genes in common wheat and its progenitor species. Scientific Reports, 2017, 7: 6641.下载
Zhao P, Wang K, Zhang W, Liu HY, Du LP, Hu HR, Ye XG*. Comprehensive analysis of differently expressed genes and proteins in albino and green plantlets from a wheat anther culture. Biologia Plantrum, 2017, 61: 255-265.下载
Zhou XH, Wang K, Du LP, Liu YW, Lin ZS, Ye XG*. Effects of the wheat UDP-glucosyltransferase gene TaUGT-B2 on Agrobacterium mediated plant transformation. Acta Physiol Plant, 2017, 39: 15.下载
Liu HY, Wang K, Xiao LL, Wang SL, Du LP, Cao XY, Zhang XX, Zhou Y, Yan YM, Ye XG*. Comprehensive identification and bread-making quality evaluation of common wheat somatic variation line AS208 on glutenin composition. Plos One, 2016, 11(1): e0146933.下载
Zhao P, Wang K, Lin ZS, Zhang W, Du LP, Zhang YL, Ye XG*. Cloning and characterization of TaVIP2 gene from Triticum aestivum and functional analysis in Nicotiana tabacum. Scientific Reports, 2016, 6: 37602.下载
尹米琦，张双喜，范春捆，王坤杨，王静，王轲，杜丽璞，叶兴国*. 不同化学试剂和处理方式加倍小麦单倍体植株的效果. 中国农业科学, 2018, 51 (5): 811-820下载
张伟, 尹米琦, 赵佩, 王轲, 杜丽璞, 叶兴国*. 我国部分主推小麦品种组织培养再生能力评价. 作物学报, 2018, 44 (2): 208-217.下载
刘会云, 王婉晴, 李欣, 王轲, 王龙, 杜丽璞, 晏月明, 叶兴国*. 小麦突变体AS208中Glu-B1位点缺失对籽粒中蛋白体形成和储藏蛋白合成与加工相关基因表达的影响. 作物学报, 2017, 43 (5): 691-700.下载
赵佩, 腾丽杰, 王轲, 杜丽璞, 任贤, 佘茂云, 叶兴国*. 小麦TaVIP1家族基因克隆、分子特性及功能分析. 作物学报, 2017, 43 (2): 201-209.下载

主要著作

中国大豆产业化现状，2000；王连铮文选，2019.
Genome Editing Technologies for Crop Improvement, 2022

授权专利

1. 叶兴国，陶莉丽，王艳丽，殷桂香，任贤，魏亦勤，杜丽璞，徐惠君，陈孝，辛志勇. 克服根癌农杆菌介导小麦幼胚褐化的转化方法及其专用培养基，2011.3，中国，专利号：ZL 200810106257.X. 2. 叶兴国，殷桂香，王艳丽，陶莉丽，徐明星，徐惠君，杜丽璞，王道文，辛志勇.一种提高小麦成熟胚再生率的培养基和农杆菌转化方法，2011.9，中国，专利号：ZL 200810106258.4. 3. 叶兴国，殷桂香，佘茂云，陈朵朵，杜丽璞，徐惠君，别小敏，孙伟珊，李欣. 一种小麦组织培养的方法，2012.6，中国，专利号：ZL200910237362.1. 4. 叶兴国，佘茂云，杜丽璞，冯晨，徐惠君，王新敏，殷桂香，李欣，别小敏. 一种植物表达载体，2012.6，中国，专利号：ZL2201010293247.9. 5. 叶兴国, 王轲, 殷桂香, 杜丽璞, 李欣, 林志珊，徐惠君, 王新敏, 周晓鸿, 张伟, 肖乐乐. 一种提高低再生力小麦基因型幼胚组织培养再生率的方法. 2013.9，中国，专利号：ZL201210085450.6. 6. 叶兴国, 王欣敏, 王轲, 徐惠君，杜丽璞, 林志珊，张伟，李欣. 一种小麦幼胚的冷冻储藏方法. 2014.8，中国，专利号：ZL201310087497. 7. 叶兴国, 王欣敏, 张伟, 王轲，杜丽璞, 赵佩，徐惠君. 一种提高小麦幼胚再生率的组织培养方法. 2015.6，中国，专利号：ZL201310397451.9. 8. 叶兴国, 王欣敏, 王轲，杜丽璞, 赵佩，张伟, 徐惠君. 提高小麦幼胚植株再生率的组织培养方法. 2015.6，中国，专利号：ZL201310397587.X. 9. 叶兴国，李仕金，林志珊，王坤杨，王静，王轲，刘畅，陈竟男，杜丽璞。用于检测簇毛麦染色体臂的成套分子标记及其应用。国家发明专利，2017.20，专利号：ZL201710970165.5. 10. 叶兴国，王轲，石田祐二，柳原千寿，刘会云，王坤杨，石磊，杜丽璞，王静，林志珊。用于改善植物的转化效率的方法和用于转化植物的方法，中国，202.11，专利号：ZL2018800377752. 11. Ye XG; Wang K; Ishida Y; Yanagihara C; Wang KY; Liu HY; Shi L; Du LP; Wang J; Lin ZS. Method for improving transformation efficiency of plant and method for transforming plant. USA patent, 2022.9, US11447784B. 12. Ye XG, Wang K, Ishida Y, Yanagihara C, Wang KY, Liu HY, Shi L, Du LP, Wang J, Lin ZS. Method for improving transformation efficiency of plant and method for transforming plant. Australia patent, 2022.12, 2018280528.