陈莉
职  称
  • 副研究员
电  话
  • 18611137236
电子邮件
  • chenli01@caas.cn
创新团队
  • 大豆育种技术创新与新品种培育
研 究 组
  • 大豆基因编辑
研究中心
  • 作物基因编辑中心
研 究 生
  • 唐猛
教育经历
  • 2004年7月,西北农林科技大学,园林专业,本科; 2007年7月,西北农林科技大学,园林植物与观赏园艺专业,硕士; 2010年7月,中国农业大学,观赏园艺专业,博士
工作经历
  • 2010年08月-2014年06月,中国农业科学院作物科学研究所博士后。 2014年07月至今,中国农业科学院作物科学研究所。
研究方向
  • 从事大豆转基因技术、基因组编辑技术和分子育种研究工作。
承担项目
  • 主持国家重点研发计划“主要农作物基因编辑种质精准创制技术”子课题和国家自然科学基金青年基金“大豆GmGRP1基因功能及其对铝胁迫应答机制的研究” 。参加农业部转基因重大专项任务“规模化转基因技术体系构建”;国家自然科学基金“蛋氨酸代谢调控及富含蛋白表达对大豆蛋白蛋氨酸积累的影响”;重点研发项目任务“主要农作物品质性状形成的分子基础”。
主要论文
  • Li Chen, Yupeng Cai, Xiaoqian Liu, Weiwei Yao, Shuiqing Wu, Wensheng Hou.The RUBY reporter for visual selection in soybean genome editing. aBIOTECH, 2024, 5: 209-213.下载
  • Yupeng Cai, Li Chen, Xiaoqian Liu,Weiwei Yao,Wensheng Hou. GmNF‐YC4 delays soybean flowering and maturation by directly repressing GmFT2a and GmFT5a expression. J Integr Plant Biol, 2024, 66(7):1370-1384.下载
  • Chen L, Yuan S, Cai YP, Yao WW, Su Q, Chen YY, Zhang JL, Hou WS*. See the color, see the seed: GmW1 as a visual reporter for transgene and genome editing in soybean. The Crop Journal; 2023, 11:311-315.下载
  • Zhang JL, Chen L, Cai YP, Su Q, Chen YY, Li M, Hou WS. A novel MORN-motif type gene GmMRF2 controls flowering time and plant height of soybean. International Journal of Biological Macromolecules; 2023, 245: 125464.下载
  • Cai YP, Chen L, Hou WS. Genome editing technologies accelerate innovation in soybean breeding. Agronomy; 2023; 13(8), 2045.下载
  • Yun JX, Wang C, Zhang FR, Chen L, Sun ZX, Cai YP, Luo YQ, Liao JW, Wang YL, Cha YY, Zhang XH, Ren Y, Wu J, Hasegawa PM, Tian CF, Su HN, Ferguson BJ, Gresshoff PM, Hou WS, Han TF, Li Xia. A nitrogen fixing symbiosis-specific pathway required for legume flowering. Science Advances; 2023, 9, eada1150.下载
  • Zhang Y, Cai YP, Sun Shi, Han TF, Chen L, Hou WS. Using Staphylococcus aureus Cas9 to expand the scope of potential gene targets for genome editing in soybean.International Journal of Molecular Science; 2022, 23:12789.下载
  • Su Q, Chen L, Cai YP, Chen YY, Yuan S, Li M, Zhang JL, Sun S, Han TF, Hou WS. Functional redundancy of FLOWERING LOCUS T 3b in soybean flowering time regulation. International Journal of Molecular Science; 2022, 23:2497.下载
  • Fu MX, Chen L, Cai YP, Su Q, Chen YY, Hou WS. CRISPR/Cas9-mediated mutagenesis of GmFAD2-1A and/or GmFAD2-1B to create high-oleic-acid soybean. Agronomy; 2022; 12(12):3218.下载
  • Jiang BJ, Chen L, Yang CY, Wu TT, Yuan S, Wu CX, Zhang MC, Gai JY, Han TF, Hou WS, Sun S. The cloning and CRISPR/Cas9-mediated mutagenesis of a male sterility gene MS1 of soybean. Plant Biotechnology Journal; 2021, 19(6): 1098-1100.下载
  • Li Chen,Yupeng Cai, Mengnan Qu,Liwei Wang, Hongbo Sun, Bingjun Jiang,Tingting Wu,Luping Liu, Shi Sun, Cunxiang Wu, Weiwei Yao,Shan Yuan, Tianfu Han, Wensheng Hou.1. Soybean adaption to high-latitude regions is associated with natural variations of GmFT2b, an ortholog of FLOWERING LOCUS T. Plant, Cell & Environment, 2020,43(4):934-944.下载
  • Yupeng Cai, Liwei Wang, Li Chen, Tingting Wu, Luping Liu, Shi Sun, Cunxiang Wu, Weiwei Yao, Bingjun Jiang, Shan Yuan, Tianfu Han and Wensheng Hou. Mutagenesis of GmFT2a and GmFT5a mediated by CRISPR/Cas9 contributes for expanding the regional adaptability of soybean. Plant Biotechnology Journal, 2020, 18(1):298-309.下载
  • Yupeng Cai, Li Chen, Xiujie Liu, Chen Guo, Shi Sun, Cunxiang Wu, Bingjun Jiang, Tianfu Han and Wensheng Hou. CRISPR/Cas9-mediated targeted mutagenesis of GmFT2a delays flowering time in soya bean. Plant Biotechnology Journal, 2018, 16(1):176-185.下载
  • Li Chen, Yupeng Cai, Xiujie Liu, Chen Guo, WeiweiYao, Shi Sun, Cunxiang Wu, Bingjun Jiang, Tianfu Han and Wensheng Hou. GmGRP-like gene confers Al tolerance in Arabidopsis, Scientific Reports, 2018, 8:13601.下载
  • Li Chen, Yupeng Cai, Xiujie Liu, Weiwei Yao, Chen Guo, Shi Sun, Cunxiang Wu, Bingjun Jiang, Tianfu Han and Wensheng Hou. Improvement of soybean Agrobacterium-mediated transformation efficiency by adding glutamine and asparagine into the culture media, International Journal of Molecular Sciences, 2018, 19, 3039.下载
  • Li Chen, Yupeng Cai, Xiujie Liu, Chen Guo, Shi Sun, Cunxiang Wu, Bingjun Jiang, Tianfu Han, Wensheng Hou. Soybean hairy roots produced in vitro by Agrobacterium rhizogenes-mediated transformation. The Crop Journal, 2018, 6(2): 162-171.下载
  • Li Chen, Bingjun Jiang, Cunxiang Wu, Shi Sun, Wensheng Hou and Tianfu Han. GmPRP2 promoter drives root-preferential expression in transgenic Arabidopsis and soybean hairy roots. BMC Plant Biology, 2014, 14: 245.下载
  • Li Chen, Bingjun Jiang, Cunxiang Wu, Shi Sun, Wensheng Hou and Tianfu Han.The characterization of GmTIP, a root-specific gene from soybean, and the expression analysis of its promoter. Plant Cell Tissue and Organ Culture, 2015, 121: 259-274.下载
  • Yupeng Cai, Li Chen, Shi Sun, Cunxiang Wu, Weiwei Yao, Bingjun Jiang, Tianfu Han and Wensheng Hou. CRISPR/Cas9-mediated deletion of large genomic fragments in soybean. International Journal of Molecular Sciences, 2018, 19, 3835.下载
  • Yupeng Cai, Li Chen, Xiujie Liu, Shi Sun, Cunxiang Wu, Bingjun Jiang, Tianfu Han, Wensheng Hou. CRISPR/Cas9-mediated genome editing in soybean hairy roots. PLoS ONE, 2015, 10(8): e0136064.下载
授权专利
  • 1.一种植物耐铝相关蛋白GmGRPL及其编码基因与应用(ZL201710473573.X)。 2.来源于大豆的根特异性启动子GmTIPp-1201及其应用(ZL201310467083.0)。 3. 来源于大豆的根特异性启动子GmTIPp-1546及其应用(ZL201310466927.X)。 4. 来源于大豆的根特异性启动子GmTIPp-253及其应用(ZL201310467039.X)。 5. 一种由系列培养基组成的试剂盒及其在大豆遗传转化中的应用(ZL201610187045.3)。 6. 生长相关蛋白GRP4在调控植物生长中的应用(ZL201510050131.5)。 7. 来源于大豆的根特异性启动子GmTIPp-2504及其应用(ZL201310466942.4)。 8. 一种植物根特异性启动子及其应用(ZL201710180228.7)。